Most of the analyzed phenolics were detected in higher amounts in the peel, compared to the mesocarp. A total of twenty compounds were quantified in the samples. The phenolic profile was determined using ultra-high performance liquid chromatography (UHPLC), coupled with a diode array detector and a TSQ Quantum Access Max triple-quadrupole mass spectrometer. The subjects of this study were seventeen samples of fruits and leaves from autochthonous apple cultivars, five international standard cultivars, and six resistant apple cultivars. Therefore, they are more likely to be used as a functional food. Additionally, they show a higher phenolic content and a stronger antioxidant activity, in comparison to commercial cultivars. Furthermore, autochthonous cultivars are characterized by a good adaptability to the local environmental conditions and represent a valuable source of genetic variability, as well as an important source of the gene pool for further breeding programs. Domesticated international (standard) apple cultivars, together with resistant apple cultivars are the core of the Serbian apple production.
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